Tirzepatide vs Liraglutide
A side-by-side comparison of Tirzepatide and Liraglutide, including efficacy data, side effects, dosing, and cost.
Feature
Tirzepatide
Liraglutide
Drug Class
GLP-1 and GIP dual receptor agonist
GLP-1 receptor agonist
Brand Names
Mounjaro, Zepbound
Saxenda, Victoza
Form
Once-weekly injection
Daily injection
Dosing
2.5 mg → 5 mg → 7.5 mg → 10 mg → 12.5 mg → 15 mg (weekly)
0.6 mg → 1.2 mg → 1.8 mg → 2.4 mg → 3.0 mg (daily)
FDA Approval
Type 2 diabetes (Mounjaro); Chronic weight management (Zepbound)
Type 2 diabetes (Victoza); Chronic weight management (Saxenda)
Efficacy
Average 20-22% body weight loss over 72 weeks (SURMOUNT trials)
Average 5-8% body weight loss over 56 weeks (SCALE trials)
Cost
$1,000-$1,500/month without insurance
$1,200-$1,600/month without insurance
Tirzepatide Side Effects
- •Nausea
- •Diarrhea
- •Decreased appetite
- •Vomiting
- •Constipation
- •Indigestion
Liraglutide Side Effects
- •Nausea
- •Diarrhea
- •Constipation
- •Vomiting
- •Headache
- •Decreased appetite
Which one should you choose?
The best medication depends on your health goals, insurance coverage, and how your body responds. Tirzepatide is a glp-1 and gip dual receptor agonist, while Liraglutide is a glp-1 receptor agonist, which can affect both efficacy and side effects.
Always consult your healthcare provider before starting or switching medications.