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GLP-1 Medications Explained: Semaglutide, Tirzepatide & More

9 min readMarch 20, 2026
GLP-1 Medications Explained: Semaglutide, Tirzepatide & More

If GLP medication names feel confusing, that is because they are.

People hear:

  • Ozempic
  • Wegovy
  • Mounjaro
  • Zepbound
  • Rybelsus
  • Saxenda
  • Victoza
  • retatrutide

Then they try to figure out which names are drugs, which names are brands, and which ones are basically the same thing.

This guide clears that up.

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The Simple Rule

The drug name is not always the same as the brand name.

That is the whole game. One drug can have multiple brand names, and each brand may be approved for a different use (like diabetes vs weight loss) or come in a different form (like injection vs pill).

Semaglutide

Drug name: semaglutide

Brand names:

  • Ozempic
  • Wegovy
  • Rybelsus

Quick version: Semaglutide is one of the best-known GLP-1 drugs. Ozempic and Wegovy are the names most people hear first. Rybelsus is the tablet version people often forget belongs in the same family.

All three contain the same active drug, but they have different FDA approvals and dose strengths. Ozempic is approved for type 2 diabetes. Wegovy is approved for weight management. Rybelsus is a daily pill approved for type 2 diabetes.

Read more: Semaglutide Guide: Ozempic, Wegovy, and Rybelsus Explained

Tirzepatide

Drug name: tirzepatide

Brand names:

  • Mounjaro
  • Zepbound

Quick version: Tirzepatide is the drug behind Mounjaro and Zepbound. It works on both GLP-1 and GIP receptors, which is why it tends to produce more weight loss than semaglutide in head-to-head trials.

Mounjaro is approved for type 2 diabetes. Zepbound is approved for weight management.

Read more: Tirzepatide Guide: Mounjaro and Zepbound Explained

Retatrutide

Drug name: retatrutide

Brand names:

  • none approved yet

Quick version: Retatrutide is one of the most talked-about investigational drugs in this category. It targets three hormone receptors (GLP-1, GIP, and glucagon), which could make it even more effective than current options. But it does not have an approved retail brand name yet.

Read more: Retatrutide Guide: What It Is, How It Works, and Why People Are Watching It

Liraglutide

Drug name: liraglutide

Brand names:

  • Saxenda
  • Victoza

Quick version: Liraglutide is an older but still important GLP-1 medication. It requires a daily injection instead of weekly. It does not get as much online attention as semaglutide or tirzepatide now, but it still matters when you are trying to understand the full drug family.

Saxenda is approved for weight management. Victoza is approved for type 2 diabetes.

Read more: Liraglutide Guide: Saxenda and Victoza Explained

Other GLP-related Names You May Run Into

These matter less for most readers right now, but they are part of the bigger picture.

Dulaglutide

  • Brand name: Trulicity

Exenatide

  • Brand names: Byetta, Bydureon

Lixisenatide

  • Brand name: Adlyxin

Why This Gets Confusing Fast

Because people often use the most famous brand name as shorthand for the whole category.

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That is why you hear people say:

  • "Ozempic" when they really mean semaglutide
  • "GLP-1" when they really mean semaglutide or tirzepatide
  • "weight-loss shot" when they do not actually know which drug they mean

The Family-Tree Version

If you want the clean mental model, use this:

Semaglutide family

  • Ozempic (diabetes)
  • Wegovy (weight loss)
  • Rybelsus (diabetes, daily pill)

Tirzepatide family

  • Mounjaro (diabetes)
  • Zepbound (weight loss)

Liraglutide family

  • Saxenda (weight loss)
  • Victoza (diabetes)

Retatrutide

  • no approved brand name yet

Common Side Effects Across GLP-1 Medications

All GLP-1 medications share similar side effects because they work on the same digestive pathways. The most common include:

  • Nausea — the most frequently reported side effect
  • Sulfur burps — rotten-egg burps from slowed digestion
  • Constipation — slowed GI motility
  • Diarrhea — especially in the first weeks
  • Headache and fatigue

Side effects are usually worst when starting or after a dose increase. For guidance on managing the ramp-up period, see GLP-1 Dosage Guide for Beginners.

Bottom Line

If you remember nothing else, remember this:

  • Semaglutide = Ozempic, Wegovy, Rybelsus
  • Tirzepatide = Mounjaro, Zepbound
  • Liraglutide = Saxenda, Victoza
  • Retatrutide = no approved brand name yet

That one map will clear up a lot of confusion.

Work with your healthcare provider to determine which medication is right for you. Individual results and experiences vary.


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Written by
J
Jeremy H.
GLP-1 Nutrition Researcher

Nutrition researcher and founder of The GLPSpot. Jeremy built this site after watching friends and family struggle with the nutritional challenges of reduced appetite on GLP-1 medications — loss of muscle mass, dehydration, and nutrient deficiencies.

Published: Last reviewed:
Medical Disclaimer: This content is for informational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition or treatment.

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